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院長ブログトップ > Is Botox Effective for Axillary Bromhidrosis?

Is Botox Effective for Axillary Bromhidrosis?

Axillary bromhidrosis refers to body odor resulting from sweat produced by specific sweat glands, particularly the apocrine glands. Let’s delve into the function of apocrine glands and explore Botox, a treatment option that has been gaining attention.


Difference between Eccrine and Apocrine

Glands Our bodies have two main types of sweat glands: eccrine and apocrine glands. They secrete eccrine sweat and apocrine sweat, respectively. Eccrine glands are found throughout the body and secrete sweat to regulate body temperature. Apocrine glands, on the other hand, are located in specific areas such as the armpits and groin, and become active during puberty. Both types of glands are controlled by the sympathetic nervous system, though they respond to different neurotransmitters. Eccrine glands are activated by acetylcholine, while apocrine glands respond to catecholamines.


What is Botox?

Botox is a product that primarily consists of botulinum toxin A, produced by the bacterium Clostridium botulinum. Botox works by inhibiting the release of neurotransmitters, particularly blocking the release of acetylcholine.


Understanding Catecholamines and Acetylcholine

Imagine participating in a relay race, passing a baton between teammates. When you pass the baton, you transfer momentum from your hand to your teammate’s. This act of passing the baton is analogous to how neurotransmitters work in neuronal communication. Acetylcholine, the neurotransmitter, is primarily used by neurons controlling eccrine glands. Botox disrupts this transmission, inhibiting eccrine gland activity. On the other hand, apocrine glands respond to a different neurotransmitter, catecholamines. Botox does not directly affect this transmission.


Application of Botox in Treating

Axillary Bromhidrosis Considering Botox’s mechanism of action, it is expected to suppress eccrine gland activity. Indeed, Botox is widely used for treating hyperhidrosis, with proven efficacy. However, since apocrine bromhidrosis is mainly caused by apocrine glands, which are controlled by catecholamines and not acetylcholine, Botox is not expected to have a direct inhibitory effect on these glands.


So, is Botox Ineffective for Axillary Bromhidrosis?

Apocrine sweat itself does not have an odor. The odor arises when N-acetyl-5-methyloornithine in the apocrine sweat, combined with fatty acids secreted by sebaceous glands, is broken down by resident bacteria (such as Corynebacterium) on moist skin. A moist environment encourages bacterial proliferation, intensifying the odor. By suppressing eccrine sweat with Botox, the skin’s moist environment improves, potentially reducing bacterial growth and subsequently alleviating the “axillary odor.”



While Botox is effective in suppressing eccrine gland activity and treating hyperhidrosis, it is not expected to have a direct effect on apocrine bromhidrosis. However, since sweating can contribute to odor, suppressing hyperhidrosis with Botox can have a beneficial effect, depending on the severity and cause of the axillary bromhidrosis. Thus, when considering Botox for axillary bromhidrosis treatment, it is crucial to consult with a specialist to ensure the selection of an appropriate treatment method.

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院長ブログトップ > All services can be offered in English

All services can be offered in English

Hi, this Kenta Motogami, CEO of Celes Medical Corporation .

Our medical group runs 3 clinics in the metropolitan area in Japan.

They are located in Aoyama (Tokyo, Minato Ward), Funabashi (Chiba Pref.) and Kawaguchi (Saitama Pref.).

We offer medical services of aesthetic plastic surgery and cosmetic dermatology.

Especially, we are good at antiaging treatments, such as Face-lifting operations, Ultherapy, and Hyaluronic-acid and Botox injections.

All services can be offered in English!

Although the regular staffs cannot communicate in English, the doctors including me can speak fluent English.

Also, feel free in asking questions in English from the following mail form.

Ask us any questions freely!


Kenta Motogami,
CEO of Celes Medical Corporation


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院長ブログトップ > Offering Safe and Secure Botox and Hyaluronic acid Injection treatments.

Offering Safe and Secure Botox and Hyaluronic acid Injection treatments.

Hi, this is Kenta Motogami, the CEO of the Celes Medical Corporation located in Tokyo Aoyama, Chiba Funabashi-shi and Saitama Kawaguchi-shi.

Today I would like to talk about the prices.

As you know, there are so many cosmetic and plastic surgery clinics all around in Japan, and you may wonder why the price differs from clinic to clinic such as the price ranges of the Botox and Hyaluronic acid(HA) injection treatment.

The major reason in this difference is because doctors can choose what types of products they use freely.

Since there are so many kinds of botox and HA products in the world, whose prices vary, the price that a clinic charges differs from the one to the other does accordingly.

The important thing I want you to keep in mind is that you should not choose and decide a clinic only based on the price. Some products are so cheap because of their poor quality and it implies that the procedures that use cheap products would be dangerous and bring unsatisfactory results.  

Everybody knows that choosing an experienced doctor is important for receiving a satisfying result, and you must know that choosing the product is as important as choosing an experienced doctor.

In Celes Medical Corporation, we only use botox and HA products in facial treatments which are authorized by the Japan Ministry of Health-Labour-Welfare. (At present, Juvederm🄬 and Botox Vista🄬 (Allergan, Inc) are the only authorized products in Japan).

It is true that many Japanese doctors are honest and dedicated, but like any other business fields, some are greedy and trying to cheat on customers.

Selecting a trusty clinic and doctor is very difficult, especially in a foreign country. Thus, if you are wavering to choose a clinic, I recommend you to phone(or mail) and ask the clinic you considering which product they offer.

I think that will help you to not being involved in trouble and make your decision easier.


Kenta Motogami, CEO of the Celes Medical Corporation
(Runs Aoyama Celes Clinic and Funabashi Chouh Clinic)


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